Pesquisa sobre: SQUALENE MONOOXYGENASE 
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Descritor Inglês:   Squalene Monooxygenase 
Descritor Espanhol:   Escualeno-Monooxigenasa 
Descritor Português:   Esqualeno Mono-Oxigenase 
Categoria:   D08.811.682.690.708.749
Definição Inglês:   The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide. 
Nota Histórica Inglês:   2006(1980); use ETHERS, CYCLIC 1970-1979 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   50664 
Identificador Único:   D050603 

Ocorrência na BVS:
 

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